Table 1

Variant	SNP ID¹	dbSNP ID	Series	Number of individuals	Common homozygote No. (expected)²	Heterozygote No. (expected)²	Rare homozygote No. (expected)²	MAF³		p-value	OR⁵ (95% CI)
Variant	SNP ID¹	dbSNP ID	Series	Number of individuals	Common homozygote No. (expected)²	Heterozygote No. (expected)²	Rare homozygote No. (expected)²	MAF³		p-value	OR⁵ (95% CI)
v1	c.-78-73C/T	N/A	Cases	96	95 (95.00)	1 (0.99)	0 (0.00)	0.01	0.96	0.12083	0.192 (0.022-1.656)
			Controls	94	89 (89.07)	5 (4.87)	0 (0.07)	0.03	0.79	0.12083	0.192 (0.022-1.656)
v2	c.-29A/C	rs4647414	Cases	96	95 (95.00)	1 (0.99)	0 (0.00)	0.01	0.96	1.3386	2.953 (0.120-73.948)
			Controls	94	94 (94.00)	0 (0.00)	0 (0.00)	0	1	1.3386	2.953 (0.120-73.948)
v3	c.816G/A	rs34671520	Cases	96	92 (94.04)	4 (3.92)	0 (0.05)	0.02	0.84	0.13638	9.000 (0.481-168.331)
			Controls	94	94 (94.00)	0 (0.00)	0 (0.00)	0	1	0.13638	9.000 (0.481-168.331)
v4	c.896+81 G/A	rs4647512	Cases	96	76 (76.15)	19 (18.70)	1 (1.15)	0.11	0.88	0.02622	2.442 (1.088-5.482)
			Controls	92	85 (85.13)	9 (8.57)	0 (0.22)	0.05	0.7	0.02622	2.442 (1.088-5.482)
v5	c.1155-38 T/C	rs4647534	Cases	96	25 (29.26)	56 (47.48)	15 (19.26)	0.45	0.08	0.73754	1.072 (0.715-1.607)
			Controls	94	30 (30.45)	47 (46.10)	17 (17.45)	0.43	0.85	0.73754	1.072 (0.715-1.607)
v6	c.1677+7C/T	N/A	Cases	96	92 (92.04)	4 (3.92)	0 (0.04)	0.02	0.84	0.13572	8.809 (0.471-164.772)
			Controls	92	92 (92.00)	0 (0.00)	0 (0.00)	0	1	0.13572	8.809 (0.471-164.772)

¹According to the nomenclature of the Human Genome Variation Society
²As expected under Hardy-Weinberg equilibrium
³Minor Allele Frequency
⁴p-value for deviation from Hardy-Weinberg equilibrium
⁵Odds Ratio (95% confidence interval)

Table 1: Sequence variations observed in FANCC gene and genotype frequencies in familial breast cancer cases and controls