| Loci
(Haplotypes) |
Haplotypes % proportion |
Total n° |
| *1/*1 |
*1/*2 |
*2/*1 |
*2/*2 |
|
ADA1/ADA2 |
Colon cancer |
71.7% |
20.7% |
7.1% |
0.5% |
198 |
| Endometrium cancer |
66.4% |
21.4% |
10.1% |
2.1% |
132 |
|
Controls |
69.7% |
22.0% |
3.9% |
4.3% |
316 |
| |
Chi square test of independence χ2 df p
Colon cancer vs endometrium cancer 3.088 3 0.378
ODDS RATIO ANALYSIS
*2/*1 vs other haplotypes/all patients vs controls OR=2.25 95% CI 1.07-4.80 (p=0.030)
*2/*2 vs other haplotypes/all patients vs controls OR=0.26 95% CI 0.072-0.868 (p=0.024) |
|
ADA1/ADA6 |
Colon cancer |
20.0% |
72.6% |
4.7% |
2.7% |
190 |
| Endometrium cancer |
19.5% |
68.7% |
2.6% |
9.2% |
136 |
|
Controls |
17.1% |
74.2% |
3.4% |
5.2% |
312 |
| |
Chi square test of independence χ2 df p
Colon cancer vs endometrium cancer
All haplotypes 7.346 3 0.062 |
|
ADA2/ADA6 |
Colon cancer |
18.9% |
63.5% |
7.0% |
10.6% |
176 |
| Endometrium cancer |
13.3% |
62.8% |
7.6% |
16.3% |
134 |
|
Controls |
14.0% |
58.3% |
6.4% |
21.5% |
272 |
| |
Chi square test of independence χ2 df p
Colon cancer vs endometrium cancer 3.181 3 0.364
ODDS RATIO ANALYSIS
*2/*2 vs other haplotypes/all patients vs controls OR=0.56 95% CI 0.354-0.891(p=0.013) |
