Characteristics

Total

ACA

Nuc

RNP

Topo

Non

Number
Respiratory symptoms
Cough
Dyspnea
KL-6 (IU/ml)
Pulmonary function testing
%Vital capacity
FEV1.0%
%DLco
Total CT score
HRCT findings
consolidation
honeycombing
honeycomb-like cysts
traction bronchoectasis
ground-glass opacity
linear opacity
reticulation
bulla
emphysema

73

18
20
930 ± 985

87.7 ± 19.4
80.2 ± 6.9
48.1 ± 16.6
6.9 ± 4.2

1
2
39
38
25
20
40
17
5

17

0*#
1*#
608 ± 382*

100.7 ± 18.1#
75.5 ± 5.6
49.6 ± 18.6
3.9 ± 2.4*#$

0
0
4*#
1*#
5
4
8
4
2

13

1*#
2*#
876 ± 575

97.3 ± 16.8
82.4 ± 6.1
51.7 ± 15.1
5.3 ± 2.6*#

0
0
7
6
6
5
9
4
2

14

4
1*#
1005 ± 1047

86.2 ± 18.6
77.8 ± 6.5
49.4 ± 10.6
7.6 ± 4.7

0
0
7
7
6
3
8
3
0

15

5
7
973 ± 458

87.3 ± 1.3
83.9 ± 5.4
49.3 ± 12.3
8.3 ± 3.4

0
1
11
12
4
4
7
2
1

14

8
9
1259 ± 1819

74.2 ± 22.1
79.7 ± 8.2
39.3 ± 20.8
10.0 ± 4.8

1
1
10
12
4
4
8
4
0
*Values are significantly different from Topo (clusters 4)
#Values are significantly different from Non (clusters 5).
$Values are significantly different from RNP (clusters 3).
Data are presented as the mean ± standard deviation or number of subjects. Categorical data and continuous data were compared using Fisher’s exact test and Mann- Whitney U-test, respectively.
Table 3: Clinical and Laboratory Characteristics of SSc patients with ILD.