| Suicide Gene Product |
Prodrug |
Drug |
| Herpes simplex virus thymidine kinase |
Ganciclovir |
Ganciclovir triphosphate |
| Varicella-Zoster virus thymidine kinase |
6-Methoxypurine arabinoside |
Adenine arabinoside triphosphate |
| Cytosine deaminase |
5-Fluorocytosine |
5-Fluorouracil |
| Purine nucleoside phosphorylase |
6-Methylpurine-2-deoxyriboside |
6-Methylpurine |
| Nitroreductase |
5-Aziridinyl-2,4-dinitrobenzamide |
5-(Aziridinyl)-4-hidroxylamine-2-nitrobenzamide |
| Beta-Galatosidase |
N-[4”-(beta-d-galactopyranosyl)-3”-nitrobenzyloxycarbonyl]daunomycin |
Daunomycin |
| Hepatic cytochrome P450-2B1 |
Cyclophosphamide and Ifosfamide |
Phosphoramide mustard and acrolein |
| Linamarase |
Linamarin |
Cyanide |
| Horseradish peroxidase |
Horseradish Indole-3-acetic acid and derivatives, paracetamol |
Free radicals |
| Carboxypeptidase A |
Methotrexate (MTX)-α-peptides |
MTX |
| Carboxypeptidase G2 |
N,N-[(2-chloroethyl) (2-mesyloxy-ethyl) amino] benzoyl-l-glutamic acid |
N,N-[(2-chloroethyl) (2-mesyloxyethyl) amino] benzoic acid |
