Figure 2: Urinary excretion of AQP2 in controls and BBS patients. Western blotting analysis of Urine AQP2/creatinine ratio after water restriction (WR) and water load (WL) in controls (C1, C2), BBS1 (PZ 2, 3, 4) and BBS10 (PZ1) patients. Each lane is representative of u-AQP2 abundance per 0.5 mg creatinine.