Patient/ gender Cerebral MRI Cervical spine MRI Thoracic spine MRI SEP VEP BAEP EMG and NCS Ophthal. exam. Neuropsych. exam 1/M Moderate cerebral cortex and cerebellum atrophy Normal imagine Slight flattening of spine Conduction disturbances in long ascending    sensory tracts with conduction block in the R posterior sensory tract. Diminished peripheral amplitude of Posterior Tibial nerve; normal conduction velocity in peripheral sensory fibres; L-N Right P100 delayed Bilateral N Sensory-motor polyneuropathy of axonal type N Slight impairment of executive functions 2/F Cortico- subcortical scar in the left parietal region Normal imagine Slight flattening of spine N Bilateral N Bilateral N Neuropathy of right common peroneal nerve N Slight impairment of executive functions

Table 2: Imaging, electrophysiological, ophthalmological and neuropsychological results of the probands. Legends: R – Right side, L – Left side, N – Normal, SEP – somatosensory evoked potentials, VEP – visual evoked potentials, BAEP – brainstem auditory Evoked potentials, EMG – electromyography, NCS – nerve conduction studies, Ophthal. exam. – ophthalmological examination, Neuropsych. exam –Neuropsychological examination.