| GENE/PRODUCT |
FUNCTION |
INHERITANCE PATTERN |
AGE OF PRESENTATION |
ANIMAL MODELS EXHIBIT |
ASSOCIATIONS |
SOURCES |
| MIB1/E3 ubiquitin- protein ligase |
Regulates myocardial cell proliferation |
Autosomal Dominant |
Adult and late childhood |
LVNC |
None |
Luxan (28) |
| G4.5/tafazzin |
Acetyl-transferase in mitochondria |
X-linked |
Early childhood |
None |
Barth Syndrome, DCM |
Towbin, Bleyl (34,39) |
| DTNA/ α-dystrobrevin |
Stabilizes plasma membrane |
Autosomal dominant |
Adult and childhood |
DCM |
None |
Ichida, Grady, Towbin (34,35,38) |
| ZASP/Z-line associated protein |
Cytoskeletal |
Autosomal dominant |
Adult and childhood |
DCM |
DCM |
Vatta (33) |
| TNNT2/TroponinT Type II |
Sarcomeric |
Autosomal dominant |
Adult and childhood |
DCM |
DCM |
Luedde, Hershberger (32,82) |
| MYH7/β-myosin heavy chain |
Sarcomeric |
Autosomal dominant |
Adult and childhood |
HCM, DCM |
HCM |
Klaassen (21) |
| MYBPC3/Myosin binding protein C |
Sarcomeric |
Autosomal recessive |
Adulthood |
HCM |
HCM |
Ripoll (37) |
MIB1 = Mindbomb Homolog 1, HCM = Hypertrophic cardiomyopathy, DCM = Dilated cardiomyopathy |
