|
CHIN ET AL (7) |
JENNI ET AL (48) |
STOLLBERGER ET AL (49) |
PETERSEN ET AL (61) |
JACQUIER ET AL (63) |
STACEY ET AL (66) |
Imaging modality |
TTE |
TTE |
TTE |
Cardiac MRI |
Cardiac MRI |
Cardiac MRI |
Quantitative criteria |
Quotient of the distance from epicardial surface to trough of trabecular recess (X) and distance from epicardial surface to peak of trabeculation (Y) ≤ 0.5 |
Non-compacted to compacted segment ratio > 2.0 |
> 3 trabeculations from apex to papillary muscle in 1 imaging plane |
Non-compacted to compacted segment ratio of >2.3 |
LV trabecular mass >20% of total LV mass |
Non-compacted to compacted ratio of >2 |
Qualitative features |
No co-existing cardiac anomalies, progressive increase in Y from base to apex |
No co-existing cardiac anomalies, 2 layered myocardium, intertrabecular recesses communicate with LV cavity demonstrated by color flow Doppler |
Intertrabecular recesses communicate with LV cavity by color flow Doppler, 2 layered myocardium |
2 layered myocardium |
2 layered myocardium |
2 layered myocardium |
Anatomic focus of measurement |
Base, papillary muscles, and apex |
Mid-lateral, mid-inferior, apex |
Apex, lateral, inferior walls |
All of LV |
All of LV |
All of LV |
Views |
Parasternal long axis, apical 4-chamber, subxyphoid |
Parasternal short axis |
Various |
Long axis |
Short axis |
Short axis |
Cardiac phase |
End-diastole |
End-systole |
Not applicable |
Diastole |
End diastole |
End systole |
Supporting data |
8 patients with LVNC compared to 8 controls found to differ significantly |
7 patients with LVNC , TTE correlated to autopsy findings, differentiated patients from 19 LVH and/or DCM controls |
No rigorous validation |
7 patients with LVNC differentiated from 125 subjects with HCM, DCM, hypertensive heart disease, aortic stenosis, and athletes |
16 patients with LVNC differentiated from 48 HCM, DCM, and healthy controls |
Associated with higher hazard ratio of clinical events than Petersen, Jacquier criteria |
Sensitivity/Specificity |
None documented |
None documented |
None documented |
86%/99% |
93.7%/93.7% |
None documented |
Limitations |
No sensitivity/specificity data, few patients studied |
No sensitivity/specificity data, few patients studied |
No rigorous validation |
May lack specificity in lower pretest probability patients |
Interobserver reproducibility of LV trabeculated mass is potentially poor |
New criteria, unknown reproducibility of findings |