| Study |
Intervention |
Intervention cases |
Time to effective antibiotics |
Mean length of stay reduction |
Mean hospital cost reduction per patient |
| Ohio State University Medical Center [23] |
Microbiology lab performs rPCR on positive cultures and pages results to both infectious PharmD (during day) and treating physician (24/7 within 10 minutes) |
156 SA bacteremia |
1.7 days, or 44% (p =.002) (MSSA cases) |
6.2 days, or 30% (p =.07) |
$21,387, or 30% (p =.02) |
| Methodist Hospital [24] |
Microbiology lab performs Mass Spec on positive cultures and notifies infectious pharmacist 24/7 who advises physician on antibiotics |
101 gram- negative bacteremia |
37 hours, or 51% (p < .001)
(all intervention patients on active therapy at 48 hours) |
2.6 days, or 22% (p = .01) |
$19,547 or, 43% (p =.009) |
