Com. pIC50 2D QSAR Model-1 2D  QSAR model-2 2D  QSAR model-3 Pred. Res. Pred. Res. Pred. Res. 1 4.5142 4.5025 0.0117 4.5760 -0.0618 4.5071 0.0071 2 3.8827 3.7289 0.1538 3.5602 0.3225 3.8565 0.0262 3 5.3914 5.3884 0.003 5.4473 -0.0559 5.4269 -0.0355 4 6.3381 6.2834 0.0547 6.3064 0.0317 6.3004 0.0377 5 5.7878 5.7266 0.0612 5.6906 0.0972 5.5156 0.2722 6 5.7544 5.7311 0.0233 5.3742 0.3802 5.6645 0.0899 7 4.585 4.3007 0.2843 4.2214 0.3636 4.2154 0.3696 8 4.0423 4.198 -0.1557 4.1349 -0.0926 4.0298 0.0125 9 4.5436 4.5063 0.0373 4.4956 0.048 4.5016 0.042 10 5.4294 5.4625 -0.0331 5.3463 0.0831 5.3545 0.0749 11 5.0118 5.167 -0.1552 5.1459 -0.1341 5.1551 -0.1433 12 4.7904 4.7947 -0.0043 4.7327 0.0577 4.7427 0.0477 13 4.5199 4.4922 0.0277 4.3954 0.1245 4.4066 0.1133 14 4.91 4.8786 0.0314 4.8533 0.0567 4.8641 0.0459 15 4.4294 4.4415 -0.0121 4.3402 0.0892 4.3485 0.0809 16 4.6716 4.6075 0.0641 4.6685 0.0031 4.6838 -0.0122 17 5.4814 5.318 0.1634 5.2743 0.2071 5.2891 0.1923 18 4.4236 4.4157 0.0079 4.4208 0.0028 4.296 0.1276 19 4.8728 4.8718 0.001 4.8432 0.0296 4.8571 0.0157 20 4.5968 4.3168 0.28 4.2768 0.32 4.2922 0.3046 21 4.6401 4.6168 0.0233 4.6745 -0.0344 4.6896 -0.0495 22 4.7904 4.713 0.0774 4.777 0.0134 4.7922 -0.0018 23 5.4559 5.3027 0.1532 5.2753 0.1806 5.2891 0.1668 24 4.7644 4.7937 -0.0293 4.6479 0.1165 4.6622 0.1022 25 6.1549 6.2882 -0.1333 6.2505 -0.0956 6.2649 -0.11 26 4.7351 4.7429 -0.0078 4.7058 0.0293 4.7216 0.0135 27 5.0087 5.1679 -0.1592 5.042 -0.0333 5.055 -0.0463 28 5.3251 5.3506 -0.0255 5.1184 0.2067 5.2311 0.094 29 4.7099 4.7151 -0.0052 4.6927 0.0172 4.6025 0.1074 30 4.7281 4.6212 0.1069 4.675 0.0531 4.6914 0.0367 31 4.7594 4.7977 -0.0383 4.7604 -0.001 4.7762 -0.0168 32 4.7721 4.7702 0.0019 4.4842 0.2879 4.6009 0.1712

Table 3: Predicted activities according to QSAR models results of 2-substituent-1H-benzimidazole-4-carboxamide.