| Label |
State variable |
| x1 |
Ins, insulin input |
| x2 |
INSR, concentration of unbound surface insulin receptors |
| x3 |
Ins:INSR, concentration of unphosphorylated once-bound surface receptors |
| x4 |
Ins2:INSR-P, concentration of phosphorylated twice-bound surface receptors |
| x5 |
surface Ins:INSR-P, i.e. concentration of phosphorylated once-bound surface receptors |
| x6 |
Intracellular INSR, i.e. concentration of unbound unphosphorylated intracellular receptors |
| x7 |
Intracellular Ins2:INSR-P, i.e. concentration of phosphorylated twice-bound intracellular receptors |
| x8 |
Intracellular Ins:INSR-P, i.e. concentration of phosphorylated once-bound intracellular receptors |
| x9 |
IRS-1, i.e. concentration of unphosphorylated insulin receptor substrate-1 |
| x10 |
IRS-1-YP, i.e. concentration of tyrosine-phosphorylated IRS1 |
| x11 |
Unactivated PI3K, i.e. concentration of unactivated PI 3-kinase |
| x12 |
IRS-1-YP:PI3K (activated), i.e. concentration of tyrosine-phosphorylated IRS1/activated PI3-kinase complex |
