|
Experimental group |
Animal # |
Control:
Vehicle (0.9% Saline) |
1-5 |
Nephrotoxicant test article:
|
|
Doxorubicin (5 mg/kg/dose)
|
21-25
|
| Doxorubicin (7.5 mg/kg/dose) |
31-35 |
| Doxorubicin (10 mg/kg/dose) |
41-45 |
| On study days 1 and 8, male Sprague-Dawley rats were administered via a lateral tail vein a bolus intravenous injection of either Vehicle (0.9% Saline) or Doxorubicin. Study termination was on day 14. |
