| |
|
Study Day 7 |
Study Day 14 |
| |
Animal# |
uMAlb/uCr (ng/mg) |
| Vehicle(0.9% Saline) |
1 |
0 |
0 |
| 2 |
0 |
0 |
| 3 |
0.04 |
0.07 |
| 4 |
0 |
0.06 |
| 5 |
0 |
0.05 |
 |
0.008 ± 0.008 |
0.04 ± 0.01 |
| Doxorubicin(5 mg/kg/dose) |
21 |
1.2 |
0.8 |
| 22 |
3.19 |
6.4 |
| 23 |
1.47 |
1.5 |
| 24 |
2.42 |
0.8 |
| 25 |
9.04 |
3.0 |
 |
3.46 ± 1.4* |
2.5 ± 1.1* |
| Fold Δ |
432.5 |
62.5 |
| Values significantly different from Vehicle (0.9% Saline) control are indicated as *p<0.05. Urinary microalbumin (uMAlb) concentrations were normalized to concurrent urinary creatinine (uCr) concentrations. |
|