| |
Genotypea |
Controls (n) |
(n=152)% |
BC (n) |
(n=144)% |
ORb |
95%CIc |
pd |
| PONI Q192R |
QQ |
143 |
94.1 |
110 |
76.4 |
1.0 |
|
1 |
| QR |
7 |
4.6 |
30 |
20.8 |
5.6 |
2.23-14.51 |
0.000 |
| RR |
2 |
1.3 |
4 |
2.8 |
2.6 |
0.40-20.83 |
0.259 |
| Q |
0.096 |
|
0.87 |
|
|
|
|
| R |
0.04 |
|
0.13 |
|
|
|
|
| PONI L55M |
LL |
130 |
85.5 |
70 |
48.6 |
1.0 |
|
1 |
| LM |
7 |
4.6 |
58 |
40.3 |
15.4 |
6.34-39.09 |
0.000 |
| MM |
15
|
9.9 |
16 |
11.1 |
2.0 |
0.87-4.53 |
0.076 |
| L |
0.88 |
|
0.69 |
|
|
|
|
| M |
0.12 |
|
0.31 |
|
|
|
|
| GLOI |
AA |
55 |
36.2 |
0 |
0 |
undefinited |
|
1 |
| AE |
20 |
13.1 |
56 |
38.9 |
undefinited |
28.911-inf |
0.000 |
| EE |
77 |
50.6 |
88 |
61.1 |
undefinited |
12.535-inf |
<0.001 |
| A |
0.43 |
|
0.2 |
|
|
|
|
| E |
0.57 |
|
0.8 |
|
|
|
|
a Genotypes with Q/R, L/M and A/E alleles, respectively
bOR, odds ratios are calculated relative to subjects with the Q/Q, L/L and A/A genotypes, respectively
c CI, confidence interval
dTwo-sided χ2 test; p< 0.05 indicates statistical significance
|
