| Clinico-pathological parameters |
Total cases
n(%) |
Q192Ra |
L55Mb |
Ala111Ec |
| QQ |
QR |
RR |
LL |
LM |
MM |
AA |
AE |
EE |
| |
144 (100) |
|
|
|
|
|
|
|
|
|
| Age at Diagnosisd |
|
|
|
|
|
|
|
|
|
|
| ≤50 |
49 (34.0) |
40 (81.6) |
7 (14.3) |
2 (4.1) |
26 (53.1) |
17 (34.7) |
6 (12.2) |
0 |
19 (38.8) |
30 (61.2) |
| 51-69 |
79 (54.9) |
56 (70.9) |
22 (27.8) |
1(12.6) |
30 (38.0) |
40 (50.6) |
9 (11.4) |
0 |
29 (36.7) |
50 (63.3) |
| ≥70 |
16 (11.1) |
14 (87.5) |
1(6.25) |
1 (6.25) |
14 (87.5) |
1 (6.25) |
1 (6.25) |
0 |
8 (50.0) |
8 (50.0) |
| |
|
pe > 0.05 |
p = 0.008 |
p > 0.05 |
| Lymph nodes |
|
|
|
|
|
|
|
|
|
|
| Positive |
34 (23.6) |
30 (88.2) |
3 (8.8) |
1 (2.9) |
4 (11.8) |
21 (61.8) |
9 (26.5) |
0 |
9 (26.5) |
25 (73.5) |
| Negative |
110 (76.4) |
80 (72.7) |
27 (24.5) |
3 (27.3) |
66 (60.0) |
37 (33.6) |
7 (6.4) |
0 |
47 (42.7) |
63 (57.3) |
| |
|
p = 0.142 |
p < 0.001 |
|
p > 0.05 |
|
| Nuclear grading |
|
|
|
|
|
|
|
|
|
|
| Low |
129 (89.6) |
108 (83.7) |
18 (13.9) |
3 (2.3) |
66 (51.2) |
48 (37.2) |
15 (11.6) |
0 |
56 (43.4) |
73 (56.6) |
| High |
15 (10.4) |
2 (13.3) |
12 (80.0) |
1 (6.7) |
4 (26.7) |
10 (66.7) |
1 (6.7) |
0 |
0 |
15(10.4) |
|
|
|
p < 0.001 |
p = 0.088 |
|
p<0.001
|
|
aGenotypes with Q/R alleles.
bGenotypes with L/M alleles
c Genotypes with A/E alleles
dThe mean ± SD ages are 59.2 ± 9.7 years for cases
e Two-sided χ2 test; p< 0.05 indicates statistical significance
|
