| Parameters |
Mild-moderate UC Group I (n=27) |
Severe UC Group II (n=23) |
Control Group Group III (n=10) |
P-value |
| -IL-23 R expression % |
|
|
| .PBMC |
6 |
12 |
1c |
0.037* |
| .LPMC |
20 |
29 |
6a |
0.001* |
| -S IL-23 (pg/ml) |
48.9 ± 7.6 |
137.4 ± 45.5b |
23.2 ± 9.4a |
<0.001* |
| -IL-23 p 19 expression |
11.6 ± 3.4 |
19.6 ± 5.5b |
3.5 ± 1.6a |
<0.001* |
| Immunohistochemestry% of +ve cells |
| P<0.05*significant between all groups; asig between patients & control; bsig between GI & GII. csig between GII & control; UC: ulcerative colitis; PBMC: peripheral blood mononuclear cells (lymphocyte) LPMC: lamina propria mononuclear cells (lymphocyte). |
