Patients characteristics |
Anti P53 positive antibodies |
Anti P53 negative antibodies |
P value |
No. (17) |
No. (122) |
Age
< or equal 56 years
>56 years |
6
11 |
80
42 |
0.016* |
Sex
Male
Female |
10
7 |
109
13 |
0.001* |
Alpha fetoprotein
<20
20-400
>400 |
-
-
17 |
10
27
85 |
0.03* |
MIF
Low
high |
10
61 |
7
61 |
0.495 |
Cirrhosis
Present
Absent |
11
6 |
45
77 |
0.732 |
Viral hepatitis
Present
Absent |
6
11 |
82
40 |
0.011* |
BCLC
A1
A2
A3
A4
B
C
D |
5
2
1
2
2
3
2 |
23
29
23
12
4
17
14 |
0.431
|
Portal vein thrombosis
Yes
No |
11
6 |
52
70 |
0.073 |
Serum bilirubin
≤1.1
>1.1 |
4
13 |
55
67 |
0.092
|
ALP
20-140IU/l
>140 IU/L |
3
14 |
44
78 |
0.133 |
AST
≤40
>40 |
3
14 |
20
102 |
0.896 |
ALT
≤40
>40 |
3
14 |
21
101 |
0.965 |
Albumin level
3.5-5.5g/L
<3.5gm/L |
4
13 |
48
74 |
0.207 |
Prothrombin time(PT)
9.5-13.5 sec
>13.5 sec |
5
12 |
77
45 |
0.008* |
Number of tumors
Single
Multiple |
6
11 |
47
75 |
0.797 |
Size of tumor
<5 cm
5 cm-less than 50%
More than 50% |
5
6
6 |
32
54
36 |
0.799
|
Hepatic metastases
No
Yes |
16
1 |
104
18 |
0.318 |
Treatment
surgical resection
radiofrequency
TACE
Chemotherapy
No treatment |
3
2
3
5
7
2 |
8
16
2
31
3
64 |
0.154
|