| Characteristics |
Overall (n=214) |
Unifocal cases (n-143) |
Multifocal cases (n=71) |
p-value |
| Age at Diagnosis |
62.8 (45-74) |
62.6 (45-74) |
63.4 (52-74) |
0.066 |
| PSA at Diagnosis |
<4 ng/ml |
12 (6.1) |
7 (5.4) |
5 (7.2) |
0.283 |
| 4-10 ng/ml |
111 (56.1) |
75 (58.1) |
36 (52.2) |
| >10 ng/ml |
75 (37.9) |
47 (36.4) |
28 (40.6) |
| n/a |
16 |
14 |
2 |
| Gleason Score |
2-6 |
50 (23.4) |
33 (23.1) |
17 (23.9) |
0.221 |
| 3+4 |
56 (26.2) |
34 (23.8) |
22 (31.0) |
| 4+3 |
83 (38.8) |
59 (41.3) |
24 (33.8) |
| 8-10 |
25 (11.7) |
17 (11.9) |
8 (11.3) |
| pT-stage |
T1a |
1 (0.5) |
1 (0.7) |
0 (0) |
0.92 |
| T1b |
6 (2.8) |
4 (2.7) |
2 (2.8) |
| T1c |
111 (51.9) |
73 (51.0) |
38 (53.5) |
| T2 |
85 (39.7) |
59 (41.3) |
26 (36.6) |
| T3 |
11 (5.1) |
6 (4.2) |
5 (7.0) |
| R-status |
R0 |
102 (47.7) |
71 (49.7) |
31 (43.7) |
0.697 |
| R1 |
49 (22.9) |
32 (22.4) |
17 (23.9) |
| RX |
63 (29.4) |
40 (28) |
23 (32.4) |
| CRPC |
Yes |
16 (8.0) |
13 (10.0) |
3 (4.3) |
0.095 |
| No |
183 (92.0) |
117 (90.0) |
66 (95.7) |
| n/a |
15 |
13 |
2 |
| PCA specific Death |
Yes |
15 (7.5) |
11 (8.4) |
4 (5.8) |
1 |
| No |
185 (92.5) |
120 (91.6) |
65 (94.2) |
| n/a |
14 |
12 |
2 |
| PCA relapse |
Yes |
55 (29.4) |
37 (30.3) |
18 (27.7) |
0.241 |
| No |
132 (70.6) |
85 (69.7) |
47 (72.3) |
| n/a |
27 |
21 |
6 |
| Secondary treatment |
Radiation |
25 (11.7) |
18 (12.6) |
7 (9.9) |
0.059 |
| Hormonal |
42 (19.6) |
31 (21.7) |
2 (2.8) |
0.283 |
| Radiation+Hormonal |
8 (3.8) |
6 (4.2) |
2 (2.8) |
1 |
|
