metabolites |
retention time |
P valuea |
A(healthy controls) |
B(cancer) |
Rb |
lactic acid |
7.069 |
0.000 |
0.0022 ± 0.0002 |
0.0031 ± 0.0008 |
0.41 |
glycerol |
12.373 |
0.038 |
0.0145 ± 0.0069 |
0.0086 ± 0.0054 |
-0.41 |
butanedioic acid |
13.801 |
0.014 |
0.0005 ± 0.0001 |
0.0004 ± 0.0001 |
-0.20 |
L-serine |
15.134 |
0.000 |
0.0014 ± 0.0004 |
0.0006 ± 0.0003 |
-0.57 |
L-threonine |
15.938 |
0.002 |
0.0011 ± 0.0002 |
0.0006 ± 0.0004 |
-0.45 |
citric acid |
28.678 |
0.026 |
0.0045 ± 0.0013 |
0.0034 ± 0.0012 |
-0.24 |
hexadecanoic acid |
34.543 |
0.000 |
0.0665 ± 0.0075 |
0.1213 ± 0.0282 |
0.82 |
|
aP values were calculated based on Mann-Whitney test (significance at P<0.05). bR value was calculated from the arithmetic mean values of each group. R=(B-A)/A. R
with a positive value indicates a relatively higher concentration present in cancer group while a negative value means a relatively lower concentration as compared to the
healthy controls. |
Table 3a: List of different metabolites identified in healthy controls and gastric cancer patients. |