metabolites retention time P valuea A(non-invasive cancers) B(invasive/metastasic cancers) Rb
glycerol 12.373 0.045 0.0119 ± 0.0052 0.0071 ± 0.0049 -0.40
butanedioic acid 13.801 0.027 0.0005 ± 0.0001 0.0003 ± 0.0001 -0.40
L-serine 15.134 0.003 0.0009 ± 0.0002 0.0005 ± 0.0003 -0.44
L-threonine 15.938 0.005 0.0010 ± 0.0002 0.0004 ± 0.0004 -0.60
L-proline 20.391 0.082 0.0041 ± 0.0013 0.0029 ± 0.0011 -0.29
myo-inositol 35.389 0.027 0.0029 ± 0.0006 0.0039 ± 0.0011 0.34
aP values were calculated based on Mann-Whitney test (significance at P<0.05). bR value was calculated from the arithmetic mean values of each group. R=(B-A)/A. R with a positive value indicates a relatively higher concentration present in invasive/metastasic cancers while a negative value means a relatively lower concentration as compared to the non-invasive cancers.
Table 3b: List of different metabolites identified in non-invasive and invasive/metastatic gastric cancer patients.