Genotype Frequency    
Variables TT (%) CC (%) T allele C allele Chi-Square p value
Histological type            
SCC 22(27.8) 21(26.6) 0.51 0.49 2.9 0.09
ADC 30(37.0) 12(14.8) 0.61 0.39    
TNM Stage            
Early Stage (I&II) 10(16.7) 26(43.3) 0.37 0.63 26.9 <0.0001
Advanced Stage (III&IV) 42(42.0) 7(7.0) 0.68 0.32    
Distant Metastasis            
Positive 35(83.3) 2(4.8) 0.89 0.11 28.4 <0.0001
Negative 17(14.4) 31(26.3) 0.44 0.56    
Family History of any Cancer            
Significant 9(47.4) 5(26.3) 0.61 0.39 0 1.0
Non Significant 43(2.8) 28(19.9) 0.55 0.45    
SCC Grade            
Well differentiated 14(32.6) 8(18.6) 0.57 0.43 2.8 0.3
Moderately differentiated 5(22.7) 8(36.4) 0.43 0.57    
Poorly differentiated 3(21.4) 5(35.7) 0.43 0.57    
ADC Grade            
Well differentiated 2(14.3) 5(35.7) 0.39 0.69 12.1 0.002
Moderately differentiated 4(17.4) 4(17.4) 0.50 0.50    
Poorly differentiated 24(53.3) 3(6.7) 0.74 0.26    
Table 5: Association and stratification analysis of CASP9 (-712C>T) polymorphism and NSCLC.