Diagnostic subgroup Area under the ROC curve (95% CI) Sensitivity at 90% Sensitivity (95% CI)
CRC 0.69 (0.60 ´ 0.78) 36% (26´47%)
Dukes´ A 0.59 (0.44 ´ 0.75) 24% (8´47%)
Dukes´ B 0.68 (0.55 ´ 0.82) 32% (16´52%)
Dukes´ C 0.74 (0.62 ´ 0.86) 47% (29´65%)
Dukes´ D 0.77 (0.62 ´ 0.93) 38% (9´75%)
Abbreviations: CI, confidence interval; ROC, receiver´operating characteristic; CRC, colorectal cancer encompassing all Duke´s stages
Table 2: Receiver operator characteristic analysis of serum Dkk´3 levels between CRC patients and healthy controls.