Figure 4: Scanning electron microscopy of one selected clinical isolates of E. coli biofilm on the surface of pegs of the microplate lid. (A) E. coli biofilm exposed to CSE1034 (significant disorganization of biofilm; a ruptured, porous and swollen cells; (B) E. coli biofilm exposed to piperacillin+tazobactam; (C) E.coli biofilm exposed to meropenem (little swollen cells in biofilm appeared); (D) control (without treatment).