Virus Family Matrix z  (°C) Power Function Parameters Temperature (°C) for Inactivation in 30 seconds Ref a b R2 1 log10 4 log10 hepatitis C virus flaviviridae culture medium 9.8† 4.26 x 1020 11.4 0.97 69 77 [33] HTLV-III retroviridae culture medium 5.6* 3.61 x 1037 21.4 1.00 59 63 [31] transmissible gastroenteritis virus coronaviridae HEPES 8.9† 4.38 x 1020 10.9 0.97 83 95 [21] Berne virus culture medium 9.6† 6.04 x 1016 9.16 0.98 73 85 [22] canine coronavirus culture medium 31† 1.23 x 109 4.92 0.86 81 107 [29] avian influenza orthomyxoviridae fat-free egg 2.1* 1.53 x 10108 61.4 0.95 58 60 [6] rabies (Pasteur) rhabdoviridae PBS 12† 3.16 x 1019 11.0 0.99 63 72 [14] rabies (ERA) PBS 8.2* 8.68 x 1021 12.4 0.99 62 70 [15] vesicular stomatitis virus PBS 8.5* 5.68 x 1020 11.9 0.97 59 66 [15] culture medium 4.4* 3.62 x 1040 23.6 1.00 54 57 [30] herpes simplex 1 herpesviridae Tris 9.0† 2.43 x 1015 8.40 0.89 74 87 [17] cytomegalovirus Tris 13† 5.10 x 1011 6.13 0.97 91 114 [17] pseudorabies virus culture medium 7.7† 1.19 x 1032 17.9 1.00 64 70 [26] variola poxviridae PBS 18† 2.07 x 1011 6.04 0.99 84 105 [16] vaccinia (Lister) buffer 10† 5.38 x 1022 12.7 0.91 65 73 [12] respiratory syncytial virus paramyxoviridae water 10* 2.17 x 1017 9.73 0.99 65 75 [18] Newcastle disease virus allantoic fluid 9.4† 5.64 x 1021 12.4 0.89 60 67 [1] fat-free egg 4.7* 5.51 x 1049 27.9 0.97 62 65 [6] HEPES, (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid); PBS, phosphate buffered saline; Tris, tris(hydroxymethyl)aminomethane. *D (decimal reduction) values used to calculate the z values and power functions were reported in the reference. †D values used to calculate the z values and power functions were estimated from the published inactivation vs. time plots.

Table 2: Heat inactivation characteristics for various enveloped viruses.