L. (V.) panamensis Antimicrobial peptide Sequence Molecular weight (Da) Natural source Secondary structure tendency* Antileishmanial activity Manganin-1 GIGKFLHSAGKFGKAFVGEIMKS 2410.4 Xenopus laevis b-sheet Manganin-2: L. (L.) donovani [14] and analogues:  L. (V.) braziliensis [13] Dermaseptin S1 ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ 3437.6 Phyllomedusa bicolor a-helix  L.(L.) amazonensis (34) L. (V.) panamensis and L.(L.) major [18] Bombinin GIGGALLSAGKSALKGLAKGLAEHFAN 2904.4 Bombina maxima a-helix L. (L.) donovani [10,12] Andropin VFIDILDKVENAIHNAAQVGIGFAKPFEKLINPK 3732.8 Drosophila melanogaster a-helix L. (V.) panamensis[8] TAP NPVSCVRNKGICVPIRCPGSMKQIGTCVGRAVKCCRKK 4073.6 Bos taurus a-helix Not described Cecropin B KWKVFKKIEKNGRNIRNGIVKAGPAIAVLGEAKAL 3818.3 Hyalophour cecropia a-helix Not described Cecropin P1 SWLSKTAKKLENSAKKRISEGIAIAIQGGPR 3321.4 Ascaris suum a-helix No activity in L. (V.) panamensis and L.(L.) major [8] Cecropin A KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK 4003.8 Hyalophour cecropia a-helix L. (V.) panamensis [8] Polystes MA VDWKKIGQHILSVL 1618.1 Polystes jadwigae Not structured Not described Melittin GIGAVLKVLTTGLPALISWIKRKRQQ 2829.7 Polystes sp. HQL-2001 a-helix  L. (L.) major [8] Tachyplesin I KWCFRVCYRGICYRRCR 2251.2 Tachypleus tridentatus β-sheet L.(V.) braziliensis, guyanensis and panamensis [13] Apamin CNCKPEPALCARRCQQH 2014.5 Apis cerana cerana a-helix Not described Pr-2 VRRRRRPR 1133.4 Oncorhynchus mykiss gairdneri a-helix L. (V.) panamensis [8] MP-8 INLKALAALAKRLL 1490.3 Vespa magnifica a-helix Not described MP- 17 INLKAKAALAKKLL 1477.3 Vespa magnífica a-helix Not described MP-X INWKGIAAMAKKLL 1539.3 Vespa simillina xanyhophera a-helix Not described CLIP LPKPPKPVSKMRMATPLLMQALPM 2674.5 MHC class II  CD74  (invariant chain) molecule [Homo sapiens] polyprolin-II (PPII) helix Endogenous peptide No antimicrobial or cytotoxic activity

Table 1: Antimicrobial peptides’ physical and antimicrobial profiles CLIP was used as a non-related peptide.