95% CI of OR     B OR Upper Lower P-value Sex 0.577 1.780 7.582 0.418 0.435 Age 0.028 1.028 1.083 0.976 0.293 MCM4 0.142 1.152 4.504 0.295 0.838 ZNF264 1.450 4.265 18.208 0.999 0.050 RNF4 -0.550 0.577 5.146 0.065 0.622 GRB2 2.009 7.456 37.131 1.497 0.014 MDM2 1.359 3.892 15.166 0.999 0.050 STAT2 -1.178 0.308 1.466 0.065 0.139 WEE1 1.264 3.540 14.784 0.848 0.083 DUSP6 2.465 11.769 40.330 3.435 <0.001 CPEB4 2.045 7.725 27.695 2.155 0.002 MMD -1.067 0.344 0.865 0.137 0.023 NF1 -1.417 0.243 1.517 0.039 0.130 IRF4 0.057 1.059 3.350 0.335 0.923 EIF2S3 -2.105 0.122 0.718 0.021 0.020 EXT2 -1.933 0.145 1.235 0.017 0.077 POLDIP2 -1.294 0.274 1.515 0.050 0.138 B: coefficient of logistic regression; OR: odds ratio; CI: confidence interval

Table 2: Multivariate analysis of colorectal cancer-related molecular markers and the discrimination model based on age, sex, and 15 genes using the logistic regression model on the training set.