95% CI
Genes used for models AUC S.E. P-value Lower Upper
DUSP6, CPEB4, EIF2S3, MDM2, MMD 0.905 0.028 <0.001 0.849 0.960
DUSP6, CPEB4, EIF2S3, MDM2 0.895 0.030 <0.001 0.838 0.953
DUSP6, CPEB4, EIF2S3 0.882 0.032 <0.001 0.820 0.945
DUSP6, CPEB4 0.855 0.032 <0.001 0.791 0.919
DUSP6 0.804 0.038 <0.001 0.730 0.879
ROC: receiver operating characteristic; AUC: area under the ROC curve; S.E.: Standard Error; CI: confidence interval. P-values for AUC were estimated using the Z test
Table 3: Discrimination power and ROC analysis of different combinations of CRC-associated genes in training set.