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Figure 5: The effects of C. zeyheri on the accumulation of R6G in C. albicans. Cells were exposed to C. zeyheri extract, fraction 3(F3), flavanoids (Flav) or the standard inhibitor reserpine (Res). Bacterial cells which were exposed to glucose had the least amount of the dye left in the cells, thus, indicating active efflux with glucose serving as a source of energy. Cells exposed to glucose and fraction 3 and flavonoids had a higher amount of dye, thus, indicating the inhibition of the efflux of the dye from the cells. Reserpine, a standard inhibitor efflux inhibitor showed the inhibition of drug efflux. |