Test sample α-helix β-structure Unordered
H(r) H(d) S(r) S(d) Turn
rhGH bulk solution 45.1% 21.9% 0.6% 2.8% 10.2% 19.5%
SR-rhGH at T0 45.6% 20.9% 0.8% 2.7% 9.6% 20.4%
SR-rhGH at T24 45.3% 20.5% 0.9% 2.7% 9.8% 20.8%
*H(r): Regular α-Helix, H(d): Distorted α-Helix, S(r): Regular β-Strand, S(d): Distorted β-Strand
Table 5: Comparison of secondary structure profiles of rhGH bulk solution and SRrhGH drug product at T0 and at T24.