Disease Strain Study References
Hypercholesterolemia Enterococcus faecium;Lactobacillus
plantarum
PH04
Randomized into two groups, oral application;For 14 days, the mice were fed a high-cholesterol diet.Subsequent 14 days, doses of probiotic were orallyadministered to half the mice/feed of mice [123]
[124]
Traveller’s diarrhea Lactobacillus casei
DN-114 001, L.plantarum
Patients were randomlyassigned to a probiotic drink or placebo, in a double-blindfashion [125]
Gastroenteritis Lactobacillus casei For the elderly was introducedprobiotic fermented milkcontaining Lactobacillus caseistrain Shirota (LcS-fermented milk) in an open case-controlstudy of its effect of (1 bottle aday) on winter-time norovirusgastroenteritis [126]
Irritable bowel syndrome (IBS) Bifidobacterium
infantis 35624
362 primary care IBS patients,with any bowel habit subtype, were randomized to either placebo or freeze-dried,encapsulated B. infantis [127]
Urogenital tract infection (UTI) Lactobacillus
rhamnosus GR-1
L. reuteri
RC-14
Was assessed in a pilot two-patientstudy in which probiotic were administered to one patient and placebo toanother, both along with antibiotics [128]
Eczema Bifidobacteriumbifidum
B. lactis
Lactococcus lactis
In a double-blind, randomized,placebo-controlled trial, a mixture of probiotic bacteria selected by in-vitroexperiments was prenatallyadministered to mothers of high-risk children and to their offspring for the first 12months of life [129]
Immunity Lactobacillusplantarum DSMZ12028 In vitro study, adhesion to intestinal epithelial cells wasevaluated using two cell lines,CaCo-2 and HT-29, throughthe plate dilution method [23]
Table 2: Different probiotic strains and their application in disease control