Groups |
SOD (U/mg) |
TAC% |
MDA(U/mg) |
GSH (U/mg) |
1st |
2.78±0.36ab |
100.00±1.01a |
104.52±4.63d |
95.25±4.15a |
2nd |
0.81±0.17d |
34.78±5.96d |
368.36±6.57a |
22.35±1.95d |
3rd |
1.90±0.15c |
68.25±5.24c |
156.53±3.85b |
62.96±8.52c |
4th |
2.25±0.14b |
80.69±7.95b |
106.38±4.10cd |
90.25±6.45b |
5th |
2.20±0.11b |
79.25±3.25bc |
110.41±3.24c |
90.58±4.07b |
|
Data presented as mean ± S.E. (n=10). Low density lipoprotein cholesterol (LDL-c)=Total cholesterol—(HDL-c+ triglyceride)/5, volatile low density lipoprotein cholesterol (VLDL-c) = Triglycerides/5, Risk ratio=Total cholesterol/high density lipoprotein cholesterol (HDL- c) Means within the same column in each category carrying different litters are significant at (P ≤ 0.05) using Duncan's multiple range tests, where the highest mean value has symbol (a) and decreasing in value were assigned alphabetically. |
Table 1: Effect of Metformin and Metformin/Cr+3 complex on Superoxide dismutase (SOD),Total antioxidant capacity (TAC), Malondialdhyde (MDA) and Glutathione reduced (GSH) in normal and diabetic rats. |