Groups SOD (U/mg) TAC% MDA(U/mg) GSH (U/mg)
1st 2.78±0.36ab 100.00±1.01a 104.52±4.63d 95.25±4.15a
2nd 0.81±0.17d 34.78±5.96d 368.36±6.57a 22.35±1.95d
3rd 1.90±0.15c 68.25±5.24c 156.53±3.85b 62.96±8.52c
4th 2.25±0.14b 80.69±7.95b 106.38±4.10cd 90.25±6.45b
5th 2.20±0.11b 79.25±3.25bc 110.41±3.24c 90.58±4.07b
Data presented as mean ± S.E. (n=10). Low density lipoprotein cholesterol (LDL-c)=Total cholesterol—(HDL-c+ triglyceride)/5, volatile low density lipoprotein cholesterol (VLDL-c) = Triglycerides/5, Risk ratio=Total cholesterol/high density lipoprotein cholesterol (HDL- c) Means within the same column in each category carrying different litters are significant at (P ≤ 0.05) using Duncan's multiple range tests, where the highest mean value has symbol (a) and decreasing in value were assigned alphabetically.
Table 1: Effect of Metformin and Metformin/Cr+3 complex on Superoxide dismutase (SOD),Total antioxidant capacity (TAC), Malondialdhyde (MDA) and Glutathione reduced (GSH) in normal and diabetic rats.