Table 4

Groups	Insulin (µU/ml) in pancreatic homogenates	Serum C-peptide (pmol/mL)
1^st	17.52±1.05a^b	3.87±1.01^ab
2^nd	6.22±0.53^e	1.12±1.03^d
3^rd	12.43±1.51^d	2.44±1.25^c
4^th	15.55±1.87^c	3.85±1.34^b
5^th	16.99±0.96b^c	3.45±1.10^b

Data presented as mean ± S.E. (n=10). Means within the same column in each category carrying different litters are significant at (P ≤ 0.05) using Duncan’s multiple range tests, where the highest mean value has symbol (a) and decreasing in value were assigned alphabetically. 1st group: control, 2nd group: STZ, 3rd group: STZ+Metformin, 4^th group: STZ +Metformin/Cr⁺³, 5^th group: STZ + CrCl₃.6H₂O.

Table 4: Effect of Metformin and Metformin/Cr⁺³ complex on insulin level and serum C-peptide in normal and diabetic rat.