Category/Gene Functionb Fold changec Microarrayd RT-PCRe
Genes encoding proteins involved in transport and binding            
LMOf2365_2305
LMOf2365_1036 		PTS system; fructose-specific; IIABC component
glycine betaine/L-proline ABC transporter; permease protein

6.5

2.1

34.3

7.7
Genes encoding proteins involved in cell envelope      
LMOf2365_0992
LMOf2365_0993
LMOf2365_1438 		D-alanyl carrier protein     
dltB protein
putative membrane protein             		5.0
3.2
3.4		 4.6
7.0
6.3
Genes encoding proteins involved in DNA metabolism            
LMOf2365_1920 recombination protein U  3.2 2.7
Genes encoding hypothetical or unknown function proteins            
LMOf2365_2230                hypothetical protein 2.3 2.4
Genes encoding proteins involved in transcription      
LMOf2365_1515             transcription elongation factor GreA          2.5 2.5
Genes encoding proteins involved in regulatory functions            
LMOf2365_1986             transcriptional regulator, Fur family          2.0 2.8
Genes encoding proteins of purines, pyrimidines, nucleosides, and nucleotides            
  LMOf2365_2584 adenylate kinase 3.4 3.2
Genes encoding proteins involved in protein synthesis      
  LMOf2365_1844 ribosomal protein L28 2.2 1.8
Genes encoding proteins involved in energy metabolism            
LMOf2365_1075
LMOf2365_1076
LMOf2365_0019 		dihydrolipoamide acetyltransferase
dihydrolipoamide dehydrogenase
cytochrome aa3 quinol oxidase, subunit IV 		2.6
2.6
1.2		 1.9
4.1
119
aOnly the genes that met the stringent criteria for being up-regulated in the ctsR mutant 2-1 of L. monocytogenes Scott A (i.e., fold change >2 fold; p<0.01) are listed here.
bGene functions are based on annotations provided by TIGR (http://cmr.jcvi.org/tigr-scripts/CMR/CmrHomePage.cgi).
cFold change indicates the transcript ratios of the ctsR mutant 2-1 between pressure treatment (450 Mpa, 3 minutes) and normal conditions as determined by microarray and real-time PCR.
dNumbers are average values from two independent experiments.
eNumbers are average values from two independent experiments.
Table 3: Genes induced in L. monocytogenes strain ScottA ctsR mutant 2-1 under pressure treatment (450 Mpa, 3minutes) as identified by microarraya and real-time PCR analysis. Gene induced only in the ctsR mutant 2-1 (not in the wildtype) are in boldface.