Organs /tissues (gm)                                                                         Uptakeof the 99mTcN-GIND
Group A (living Streptococcus pneumoniae) Group B (heat killed Streptococcus pneumoniae)
  30 60 90 120 30 60 90 120
Infected muscle 6.25 ± 0.18 12.00 ± 0.20 15.20 ± 0.17 12.15 ± 0.16 2.50 ± 0.15 3.00 ± 0.18 3.50 ± 0.16 3.00 ± 0.16
Inflamed muscle 4.50 ± 0.16 4.00 ± 0.18 3.50 ± 0.14 3.00 ± 0.17 4.25 ± 0.18 4.00 ± 0.14 3.50 ± 0.17 3.00 ± 0.15
Normal muscle 2.50 ± 0.14 3.00 ± 0.16 2.50 ± 0.19 2.50 ± 0.20 2.50 ± 0.18 3.00 ± 0.16 2.50 ± 0.17 2.50 ± 0.20
Blood 18.55 ± 0.20 10.80 ± 0.16 8.00 ± 0.00 4.75 ± 0.15 19.00 ± 0.17 10.65 ± 0.16 7.90 ± 0.18 4.50 ± 0.20
Liver 19.00 ± 0.16 11.50 ± 0.20 9.30 ± 0.18 6.00 ± 0.15 18.40 ± 0.20 11.45 ± 0.15 9.10 ± 0.20 6.10 ± 0.14
Spleen 8.70 ± 0.18 7.50 ± 0.20 6.40 ± 0.14 4.20 ± 0.18 8.65 ± 0.14 7.30 ± 0.17 6.25 ± 0.20 4.00 ± 0.18
Kidney 8.00 ± 0.14 17.40 ± 0.20 20.10 ± 0.16 23.75 ± 0.14 8.25 ± 0.20 19.00 ± 0.14 21.30 ± 0.17 24.00 ± 0.00
Stomach & intestines 8.50 ± 0.20 7.45 ± 0.16 6.75 ± 0.12 4.10 ± 0.00 8.75 ± 0.14 8.00 ± 0.18 7.10 ± 0.19 4.30 ± 0.18
Table 1: Biodistribution of the 99mTcN-GIND complex in artificially infected MWR with Streptococcus pneumoniae.