Organs &body fluids Percent I.D./gram organ Time post injection 15 min 1/2 hr 1 hr 2 hr Blood 12.2 ±1.10 11.6 ± 0.20* 7.2 ± 0.04*    3.7 ± 0.30* Bone   2.0 ± 0.05  3.2 ± 0.10* 2.3 ± 0.10* 2.2 ± 0.2 Muscle   0.5 ± 0.01  1.5 ± 0.02* 1.3 ± 0.10    0.7 ± 0.02* Liver   5.1 ± 0.05  6.5 ± 0.15* 3.5 ± 0.06*    2.0 ± 0.02* Lung   4.3 ± 0.10  6.5 ± 0.12* 3.2 ± 0.20*    2.1 ± 0.01* Heart   8.2 ± 0.80  6.9 ± 0.30* 5.2 ± 0.01*    1.8 ± 0.04* Stomach 5.2 ± 0.90 7.2 ± 0.60 7.6 ± 0.16*     7.7 ± 0.2 Intestine   5.4 ± 0.50  7.2 ± 0.30* 3.1 ± 0.10*    1.9 ± 0.03* Kidney   6.9 ± 0.40  9.0 ± 0.600 4.1 ± 0.30*    2.1 ± 0.06* Spleen   1.7 ± 0.02  3.1 ± 0.14* 3.0 ± 0.16    1.1 ± 0.20*

*significantly different from the previous value of each organ using unpaired Student’s t-test (P<0.05).

Table 2 : Biodistribution of 99mTc-losartan in normal mice. Mean ± SD (mean of 10 experiments).