The unit on x-axis is month, 0 indicates the time of HCC diagnosis; on y-axis for AFP is ng/mL; AFP-L3 is %; and DCP is ng/mL. Six of the 7 patients with multiple serum specimens showing elevated AFP-L3 >5% one year prior to MRI confirmation, while only 2 with AFP >20 ng/mL and 1 with DCP >7.5 ng/mL (AFP-L3 superior to others).

Figure 1: Change of AFP, AFP-L3 and DCP Value Overtime before HCC Diagnosis.