SCCmec Type   Antimicrobial Classification* Clonal MRSA isolate Date of isolation Infection site PVL resistance   type wb94 may/07 Furuncle IVc pos Ery CA-MRSA OSPC wb95 may/07 Abscess IVc pos Ery CA-MRSA OSPC wb100 jun/07 Cellulitis IVa neg   CA-MRSA USA300 wb102 jul/07 Sputum IVb neg Gen HA-MRSA USA300 wb103 set/07 Folliculitis IVc pos Ery CA-MRSA OSPC wb104 nov/07 Cellulitis IVc pos Ery CA-MRSA OSPC wb105 nov/07 Abscess IVc pos Ery CA-MRSA OSPC wb106 dez/07 Cellulitis IVc neg Ery CA-MRSA USA400 wb108 mar/08 Cellulitis IVc pos Ery CA-MRSA OSPC a4 abr/08 Varicella vesicle IVa neg Cip, Ery HA-MRSA USA300 wb116 mai/08 Abscess IVc pos Ery, Gen CA-MRSA OSPC wb117 mai/08 Nasal IVc neg Ery CA-MRSA USA400 wb120 jun/08 Blood IVb neg Cli, Ery, Gen CA-MRSA USA300 wb121 jul/08 Cellulitis IVb pos Ery, Gen HACO-MRSA OSPC wb122 jul/08 Folliculitis IVc pos Ery, Gen CA-MRSA OSPC wb124 ago/08 Sputum IVb neg Ery, Gen CA-MRSA USA300 wb128 set/08 Cellulitis IVc pos Ery CA-MRSA USA300 wb129 set/08 Folliculitis IVc pos Ery CA-MRSA OSPC wb130 out/08 Furuncle IVc pos   CA-MRSA OSPC wb131 nov/08 Cellulitis IVc pos Ery CA-MRSA OSPC wb133 mai/09 Blood IVc neg Cip, Gen HA-MRSA *** wb134 mai/09 CSF** IVc neg Cip CA-MRSA *** wb135 mai/09 Furuncle IVc pos Cli, Ery CA-MRSA OSPC wb141 ago/09 Abscess IVc pos Ery HACO-MRSA OSPC wb142 set/09 Fistula IVc pos   HACO-MRSA OSPC *according to criteria proposed by Klevens et al. 2007. ** Cerebral spinal fluid *** distinct from the clones used for comparison HACO-MRSA - health care-associated community onset: caseswith a health care risk factor but with a culture obtained ≤ 48 hours after hospital admissiom HO-MRSA - hospital-onset: cases with culture obtained > 48 hours after admission regardless of whether they also had other health-care risk factors CA-MRSA - community-associated: cases without documented heath care risk factors recovered at an outpatient setting or < 48 hours of hospital admission

Table 1: Phenotypic and genotypic analysis of MRSA isolates