Invariant Peptide Amino Acid Positions Median Score Mean Score Standard Deviation Minimum Score Maximum Score peptide1 83-94 0.4575 0.5220 0.3644 -0.0580 1.0510 peptide2 99-123 0.8440 0.6217 0.5561 -0.3740 1.3980 peptide3 157-173 -0.8150 -0.9653 0.4250 -1.7700 -0.4040 peptide4 556-581 -0.3385 -0.3672 0.6510 -1.4410 0.6060 peptide5 603-623 0.3300 0.3065 0.3597 -0.4390 0.8030 peptide6 642-657 0.3430 0.3054 0.2380 -0.2300 0.7560

Table 2: Predicted B-cell Epitope Scores of Invariant Peptides of Length 12-mer or Greater in ZEBOV and SEBOV Ebola Virus GP1,2 Protein. Amino acid sequences of the six invariant peptides are given in the Results text.