Diagnosis test Sensitivity (%) Specificity (%) PPV (%) NPV (%) 18R rRNA qPCR assay  -Blood 50 80 73 59 GM-EIA 38 100 100 61 Combination  (PCR 18s + GM-EIA) 71 80 79 73 5.8S rRNAqPCR assay -Blood 90 40 61 80 GM-EIA 38 100 100 61 Combination  (PCR 5.8s + GM-EIA) 95 40 63 89 PCR: Polymerase Chain Reaction; PPV: Positive Predictive Value; NPV: negative predictive value; qPCR: quantitative Real Time PCR; GM: Galactomannan.

Table 5: Performance of the combination of galactomannan test and PCR tests with primers rDNA 18s and rDNA 5.8s in the diagnosis of IA.