Note: Ordinate=sum(H) in bits, abscissa=amino acid position. SP=signal peptide, RBD=receptor binding domain, GC=glycan cap, MLD=mucin-like domain, FL=fusion loop. Vertical red line denotes the cleavage site of GP1,2 precursor protein into GP1 and GP2 proteins by furin peptidase at amino acid 501 [10].

Figure 1: Summed Information Entropy (H) and Functional Organization of ZEBOV Glycoprotein GP1,2.