| Sl. No. |
Vaccine |
Immunostimulants |
| 1. |
Prophylactic for long duration with only one or two treatments. |
Prophylactic for short duration, require more treatments. |
| 2. |
Efficacy of vaccine is excellent |
Efficacy of immunostimulants is good |
| 3. |
Limited spectrum of activity. |
Wide spectrum of activity |
| 4. |
No toxic side effects |
No toxic side effects |
| 5. |
No accumulation of toxic residues |
No accumulation of toxic residues |
| 6. |
No environmental impact |
No environmental impact |
| 7. |
Enhance specific and nonspecific immune response |
Mainly enhance nonspecific immune system of larvae before specific immune system matures. |
| 8. |
Difficult to vaccinate larvae of fish and shrimp |
Easy to vaccinate larvae of fish and shrimp |
| 9. |
Costly |
Cost effective |
