Figure 10: 2D-DOSY spectrum of 4:1 POPC/POPG SUVs and 1 mg of compound 53. The broad peak on the y-axis and the broad cross peaks also on the x-axis indicate that the exchange rate between the SUV bound phospholipids and the monomeric form of the phospholipids is high. This indicates that the binding of the AMP to the SUV is disrupting the structure of the liposome.