Figure 2: Survival of B16F10 melanoma cells treated with paclitaxel or the DDMC-paclitaxel complex. A) Survival of B16F10 melanoma cells treated with paclitaxel or the DDMC-paclitaxel complex for 48 hours determined using the MTT (WST8) method. B) B Tubulin polymerization and cell death (Cd) rates can be expressed by enzymatic kinetic parameters. Relationship between Cd and paclitaxel concentration. C) The mean tumor volumes increase rate in the PTX, saline, DDMC/PTX4 (size: 50 nm) and DDMC/PTX5(size: 290 nm) groups.