Experimental group Product(s) administered (p.o.) Dose Ulcer index (U.I.) [median (min-max)]
stomach esophagus
IBU-NP group (n=7) IBU loaded-nanoparticles 12 mg/kg 1.6 (4.5-0.0) 0.9 (2-0)
IBU group (n=3) IBU in aqueous solution 12 mg/kg 2.0 (2.5-1) 1.0
Control group (n=2) PBS 7.4 0 0.0 0.0
Normal rat (n=1) water 0 0.0 0.0
Table 2: Ulcer index in the stomach and the esophagus in the different groups studied.