Cmáx (μg/ml) tmáx (min) AUC0-90 (μg/ml/min) DG4.5-Risp 3.42 ± 0.78 15 80,28 Risp 7.97 ± 1.72 15 395,90

Table 1: Pharmacokinetic parameters after Risp oral treatment in the free form and as the DG4.5-Risp complexes (n=6).