Polymer Micelle diametera %DLb (wt.%) %EEc (wt.%) %DLd (mol%) CACe (μg/ml) Blank micelles curcumin micelles (PEG775)2-PCL4700 47.3±3.6 42.9±0.5 6.0±0.1 60.0±0.8 50.5±0.3 1.32 (PEG775)2-PCL7800 45.9±0.6 40.9±0.6 4.6±0.1 48.7±1.4 55.3±0.7 - (PEG775)2-PCL8800 63.3±2.4 53.7±1.6 4.6±0.1 48.5±0.6 57.7±0.3 - (PEG775)2 -PCL10,300 57.8±1.8 46.0±1.3 5.3±0.1 55.5±0.6 64.1±0.2 - (PEG775)2-PCL12,600 55.3±0.9 45.8±1.0 5.2±0.0 54.4±0.2 66.7±0.1 0.39 (PEG775)2-PCL14,200 46.6±0.9 56.7±2.9 6.5±0.0 65.0±0.3 73.5±0.1 0.35 Polymer Micelle diametera %DLb (wt.%) %EEc (wt.%) %DLd (mol%) CACe (μg/ml) Blank micelles curcumin micelles (PEG775)2-PCL4700 47.3±3.6 42.9±0.5 6.0±0.1 60.0±0.8 50.5±0.3 1.32 (PEG775)2-PCL7800 45.9±0.6 40.9±0.6 4.6±0.1 48.7±1.4 55.3±0.7 - (PEG775)2-PCL8800 63.3±2.4 53.7±1.6 4.6±0.1 48.5±0.6 57.7±0.3 - (PEG775)2 -PCL10,300 57.8±1.8 46.0±1.3 5.3±0.1 55.5±0.6 64.1±0.2 - (PEG775)2-PCL12,600 55.3±0.9 45.8±1.0 5.2±0.0 54.4±0.2 66.7±0.1 0.39 (PEG775)2-PCL14,200 46.6±0.9 56.7±2.9 6.5±0.0 65.0±0.3 73.5±0.1 0.35

aHydrodynamic diameter (nm), mean of three measurements ± SD

mean of three measurements ± SD

mean of three measurements ± SD

mean of three measurements ± SD

eCritical association concentration in water

Table 2: Properties of A2B miktoarm polymers based micelles with or without curcumin.

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