Sample 1H-NMR data (δ) Methyl-pioglitazone 1H-NMR (δ , d6-DMSO): 3.91 (CH2CH2), 6.50-6.62 (ArH), 7.49–7.55 (ArH), 7.78 (C6H4CH===C) β-CD 1H-NMR (δ , d6-DMSO): 3.42-4.15 (Aliphatic C-H), 2.78-3.25 (O-H); Methyl-pioglitazone-β-CD 1H-NMR (δ , d6-DMSO): 7.05-7.12 (ArH), 2.12-3.43 (Aliphatic C-H) 165.5, 167.9

Table 3: 1H-NMR data of pioglitazone, β-CD, and pioglitazone-β-CD inclusion complex.