| Variable |
Pediatric Patients |
Adult Patients |
| Number (n) |
90 |
104 |
| Age (years)* |
10.2 ± 5.6 |
33.3 ± 10.5 |
| Genotype |
| SS |
61 (68%) |
74 (71%) |
| SC |
23 (25%) |
20 (19%) |
| SB(0 or +) |
6 (7%) |
10 (10%) |
| Vitamin D (ng/mL)* |
17.2 ± 9.5 |
13.6 ± 7.9 |
| <11 |
29 (32%) |
51 (49%) |
| 11-30 |
50 (56%) |
49 (47%) |
| >30 |
11 (12%) |
4 (4%) |
| Baseline Hgb* |
9.2 ± 1.3 |
9.1 ± 1.8 |
| Reticulocyte count (%)* |
8.3 ± 4.9 |
8.2 ± 4.7** |
| LDH* |
414 ± 159** |
375 ± 205** |
| Hydroxyurea (HU) |
| Yes |
24 (24 HbSS) |
not evaluated |
| No |
66 (37 HbSS) |
not evaluated |
*Values for indicated fields are expressed as means ± SD. All other values reflect number of patients, with percentages in parentheses.
**n for these values are different from the total number of patients: 102 for adult reticulocyte count; 63 and 85 for LDH in pediatric and adult cohorts, respectively. Conversion factor for 25-OH vitamin D (ng/mL to nM) is 2.496. |
|
