No. of Subjects 422 Age 68 (± 10) Male 350(83%) Smoker 312(74%) Body mass index (kg/m2) 28.0 (± 4.7) Waist circumference (cm) 100.5 (± 12.5) Diabetes 114 (27%) Hypertension 287(53%) Statin 248 (59%) Beta blocker 241 (57%) LDL cholesterol (mmol/l) 2.5 (± 1.0) HDL cholesterol (mmol/l) 1.3 (±0.4)

Table 1: Baseline characteristics of study population. Results are number (percent) or mean (standard deviation) as appropriate.