Reactive oxygen

Symbol

Half life (in sec)

Reactivity / Remarks

Superoxide

O2

0-  6 s          

Generated in mitochondria, in cardiovascular system and others

Hydroxyl radical

•OH

10-9 s

Very highly reactive, generated during iron overload and such conditions in our body

Hydrogen peroxide

H2O2

stable

Formed in our body by large number of reactions and yields potent species like OH

Peroxyl radical

ROO

s

Reactive and formed from lipids, proteins, DNA, sugars etc. during oxidative damage

Organic hydro peroxide

ROOH

stable

Reacts with transient metal ions to yield reactive species

Singlet oxygen

1O2

10-6 s

Highly reactive, formed during photosensitization and chemical reactions

Ozone

O3

s

Present as an atmospheric pollutant, can react with various molecules, yielding 1O2

Table 1: Reactive oxygen species of biological interest.